Table 1

Overview of studies on MS risk in children of MS patients
Author Year Country Number of patients Estimated lifetime risk in general population (%) Male MS patients Female MS patients
Age-adjusted risk for children Relative risk for children Age-adjusted risk for children Relative risk for children
Nielsen et al. [20] 2005 Denmark 8205 Men, 0.3; women, 0.5 - Daughter 7.5 - Daughter 4.5
Son 7.5 Son 9.5
Total 7.5 Total 6.3
Prokopenko et al. [23] 2003 Italy (Sardinia) 313 0.157 - - Total 3.19 Total 20.3
Carton et al. [22] 1997 Belgium 674 0.175 Total 1.51 Total 8.6 Total 1.87 Total 10.7
Robertson et al. [21] 1996 UK 674 0.3 (men, 0.13; women, 0.66) Daughter 7.12 Daughter 10.8 Daughter 1.74 Daughter 2.6
Son 2.54 Son 19.5 Son 0.0 Son 0.0
Total 4.91 Total 16.4 Total 0.81 Total 2.7
Sadovnick and Baird [24] 1988 Canada 815 0.1 Daughter 5.13 Daughter 51.3 Daughter 4.96 Daughter 49.6
Son 0.0 Son 0.0 Son 0.0 Son 0.0
Total 2.47 Total 24.7 Total 2.58 Total 25.8

Borisow et al.

Borisow et al. EPMA Journal 2012 3:9   doi:10.1186/1878-5085-3-9

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